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Having just witnessed the death of her husband Jack from an incurable neurological disease, Anne Turner (Julie Walters) is diagnosed with a near identical illness. With determined rationality, Anne's answer is that once her illness has reached a critical point, she will take her own life. And she needs her children's support. But the more her son and two daughters struggle to gain consensus over their mother's desire to die, as they struggle to find another way through, the further they pull apart. From Jessica's silent recriminations to Sophie's stubborn practicality, the magnitude of the situation threatens to tear the family to pieces. Anne must also face the fury of her best friend Claire – whose opposing views bring them into direct and vocal conflict.